Addyi is the first and only FDA-approved treatment for HSDD, indicated for women under 65.
PRESCRIBING ADDYI JUST GOT EASIER
Addyi is the first and only FDA-approved treatment for HSDD, indicated for women under 65.
Addyi is the #1 Prescribed Treatment for HSDD.1
Did you know that nearly 3 out of 4 women are waiting for you to start the conversation about sexual health?
Keys to patient success
- Prescribe Addyi through PhilRx for the guaranteed lowest price, as little as $20 per month with commercial insurance coverage, and free home delivery (Search “PhilRx” in the EMR’s retail pharmacy finder)
- Counsel Patient to Take One 100mg Addyi Tablet Every Night at Bedtime
- If patient skips a dose, wait until the next night to resume taking Addyi.
- Addyi is dosed at bedtime because administration during waking hours increases the risks of hypotension and syncope.
- Take Addyi Once Daily For at Least 8 Weeks
- Allow at least 8 weeks for benefits to become noticeable.
- Some women may start to notice the effects of Addyi within a few weeks- an increase in sexual desire, more sexually satisfying events, and a decrease in distress. Discontinue Addyi if your patient does not see any improvements after 8 weeks.
- Consistency is key to achieving the best results.
Addyi is the #1 Prescribed Treatment for HSDD.1
Did you know that nearly 3 out of 4 women are waiting for you to start the conversation about sexual health?
Keys to patient success
- Prescribe Addyi through PhilRx for the guaranteed lowest price, as little as $20 per month with commercial insurance coverage, and free home delivery (Search “PhilRx” in the EMR’s retail pharmacy finder)
- Counsel Patient to Take One 100mg Addyi Tablet Every Night at Bedtime
- If patient skips a dose, wait until the next night to resume taking Addyi.
- Addyi is dosed at bedtime because administration during waking hours increases the risks of hypotension and syncope.
- Take Addyi Once Daily For at Least 8 Weeks
- Allow at least 8 weeks for benefits to become noticeable.
- Some women may start to notice the effects of Addyi within a few weeks- an increase in sexual desire, more sexually satisfying events, and a decrease in distress. Discontinue Addyi if your patient does not see any improvements after 8 weeks.
- Consistency is key to achieving the best results.
Addyi affects
dopamine, norepinephrine, and serotonin3
Addyi affects
dopamine, norepinephrine, and serotonin3
3. The specific mechanism of action is not fully understood.
if she’s saying these things, it may be hsdd
Learn to recognize the signs of HSDD in your patients.4
I feel stressed due to my low desire
i am no longer interested in masturbating
i don’t have sexual thoughts anymore
it’s harder for me to become aroused
i have little to no sexual desire
if she’s saying these things, it may be hsdd
Learn to recognize the signs of HSDD in your patients.4
I testified at the FDA 10 years ago when Addyi was approved — a watershed moment that validated women’s sexual health with the first FDA approved option to treat women with frustrating low libido. In my practice, it opened conversations that had long been silenced and gave patients hope.
Dr. Alyse Kelly-Jones, Ob/Gyn
I testified at the FDA 10 years ago when Addyi was approved — a watershed moment that validated women’s sexual health with the first FDA approved option to treat women with frustrating low libido. In my practice, it opened conversations that had long been silenced and gave patients hope.
Dr. Alyse Kelly-Jones, Ob/Gyn
IN THEIR WORDS
real experiences. real reviews.
IN THEIR WORDS
real experiences. real reviews.
“Addyi has helped me get my libido back. My sweet husband has been so patient with me for years now – I dreaded his advances – I can’t tell you how wonderful it has been to want sex again.”
Elizabeth, 45, Addyi patient
“When I heard about Addyi, I was curious if it would work for me. After only a few weeks on Addyi I’m already thinking about and wanting sex again!”
Caroline, 60, Addyi patient
“I used to dread going to bed with my husband, because I was never in the mood… he thought it was his fault. We were really struggling. Then we found Addyi!”
Kendall, 31, Addyi patient
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MEDICAL INFO:
844-746-5745 x 4
medicalaffairs@sproutpharma.com
- IQVIA Monthly Total Prescriptions Volume Data Comparing Addyi vs Vyleesi in the US. April 2024–April 2026
- Ryan KL, Arbuckle-Bernstein V, Smith G, Phillips J. Let’s Talk About Sex: A Survey of Patients’ Preferences When Addressing Sexual Health Concerns in a Family Medicine Residency Program Office. PRiMER. 2018;2:23. https://doi.org/10.22454/PRiMER.2018.728252
- Stahl SM, et al. Multifunctional pharmacology of flibanserin: possible mechanism of therapeutic action in hypoactive sexual desire disorder. J Sex Med. 2011;8:15-27
- Www.medicalnewstoday.com, 30 Nov. 2022, www.medicalnewstoday.com/articles/hypoactive-sexual-desire-disorder#overview
- Gerstenberger EP, Rosen RC, Brewer JV, et al. Sexual desire and the Female Sexual Function Index (FSFI): a sexual desire cutpoint for clinical interpretation of the FSFI in women with and without hypoactive sexual desire disorder. J Sex Med. 2010;7(9):3096–3103.
- Rosen R, Brown C, Heiman J, et al. The Female Sexual Function Index (FSFI): A multidimensional self-report instrument for the assessment of female sexual function. J Sex Marital Ther. 2006; 26:2, 191-208.
- Addyi Prescribing Information.
- https://www.fda.gov/drugs/drug-interactions-labeling/drug-development-and-drug-interactions-table-substrates-inhibitors-and-inducers
- Clayton AH, Harry AC, Yuan J, et al. Safety of flibanserin in women treated with antidepressants: A randomized, placebo-controlled study. J Sex Med 2018;15(1):43-51.
- Arnow BA, Millheiser L, Garrett A et al. Women with hypoactive sexual desire disorder compared to normal females: a functional magnetic resonance imaging study. Neuroscience 2009;158:484-502.
- Woodard TL, Nowak NT, Balon R et al. Brain activation patterns in women with acquired hypoactive sexual desire disorder and women with normal sexual function: a cross-sectional pilot study. Fertil Steril 2013;100:1068-1076.
- Bianchi-Demicheli F, Cojan Y, Waber L, et al. Neural basis of hypoactive sexual desire disorder in women: an event-related fmri study. J Sex Med. 2011;8:2546-2559.
- Holstege G. How the emotional motor system controls the pelvic organs. Sex Med Rev. 2016: 4;303-328.
- Kingsberg SA. Attitudinal survey of women living with low sexual desire. J Women’s Health. 2014;23(10):817-23
- Clayton AH, Brown L, Kim NN. Evaluation of safety for flibanserin. Expert Opin Drug Saf. 2020;19(1):1-8. doi:10.1080/14740338.2020.1707804
- Goldfischer ER, Breaux J, Katz M et al. Continued efficacy and safety of flibanserin in premenopausal women with hypoactive sexual desire disorder (HSDD): Results from a randomized withdrawal trial. J Sex Med.2011; 8:3160-3172.
- Jayne C, Simon JA, Taylor LV, Kimura T, Lesko LM; SUNFLOWER study investigators. Open-label extension study of flibanserin in women with hypoactive sexual desire disorder. J Sex Med. 2012;9(12):3180-3188. doi:10.1111/j.1743-6109.2012.02942.x
- Kornstein SG, James JA, Apfel SC, et al. Effect of flibanserin treatment on body weight in premenopausal and postmenopausal women with hypoactive sexual desire disorder: A post hoc analysis. J Women’s Health. 2017;26(11):1161-1168.
Important Safety Information
What is the most important information I should know about ADDYI?
ADDYI can cause severe low blood pressure and fainting (loss of consciousness). Your risk is higher if you drink alcohol close to your dose. Do not take ADDYI with certain medicines or if you have liver problems. To lower your risk of low blood pressure and fainting:
- Do not drink alcohol close to the time you take ADDYI. Skip your dose if you had 3 or more drinks before bedtime. Wait at least 2 hours after 1–2 alcoholic drinks before taking ADDYI. After taking ADDYI, do not drink alcohol until the next day
- Talk to your doctor about the medicines and supplements you take and before starting any new ones
- Do not take ADDYI if you have liver problems
If you feel dizzy or lightheaded after taking ADDYI, lie down right away. Get medical help if symptoms do not go away.
Who should not take ADDYI?
Do not take ADDYI if you:
take certain medicines that increase ADDYI levels in your blood (including some treatments for HIV, fungal infections, antibiotics, hepatitis C, heart conditions, or depression such as nefazodone)
- have liver problems
- are allergic to ADDYI
What should I tell my doctor before taking ADDYI?
Tell your doctor about all your medical conditions, including if you:
- drink alcohol, use drugs, or have a history of substance abuse
- have ever had depression or other mental health conditions
- have low blood pressure or a condition that can cause it
- are pregnant, planning pregnancy, or breastfeeding
Tell your doctor or pharmacist about all medicines and supplements you take, as they may interact with ADDYI.
What should I avoid while taking ADDYI?
- Do not drink alcohol close to your dose
- Do not drive or operate machinery for at least 6 hours after taking ADDYI
- Do not drink grapefruit juice
- Do not take supplements such as St. John’s Wort, ginkgo, or resveratrol, or certain medicines like cimetidine, without talking to your doctor
What are the possible side effects of ADDYI?
ADDYI can cause serious side effects, including:
- See “What is the most important information I should know about ADDYI?”
- sleepiness
- low blood pressure and fainting
The most common side effects include:
- dizziness
- nausea
- tiredness
- trouble sleeping
- dry mouth
This is not a complete list of side effects. Call your doctor for medical advice.
What is ADDYI?
ADDYI is a prescription medicine used to treat hypoactive (low) sexual desire disorder (HSDD) in women < 65 years of age who have not had problems with low sexual desire in the past, no matter the type of sexual activity, situation, or sexual partner, and it is troubling to them. Their low sexual desire is not due to a medical or mental health problem, problems in the relationship, medicine or other drug use.
ADDYI is not for use in men or to improve sexual performance.